Results

Mean Differences (n, M, SD)

need finite 'xlim' values

Random-Effects Model (k = 8)
 EstimateseZpCI Lower BoundCI Upper Bound
Intercept-0.9310.480-1.940.052-1.8710.010
......
Note. Tau² Estimator: Restricted Maximum-Likelihood
[3]

 

Heterogeneity Statistics
TauTau²dfQp
1.3301.77 (SE= 0.9849 )97.11%34.599.7.000139.810< .001

 

The analysis was carried out using the standardized mean difference as the outcome measure. A random-effects model was fitted to the data. The amount of heterogeneity (i.e., tau²), was estimated using the restricted maximum-likelihood estimator (Viechtbauer 2005). In addition to the estimate of tau², the Q-test for heterogeneity (Cochran 1954) and the I² statistic are reported. In case any amount of heterogeneity is detected (i.e., tau² > 0, regardless of the results of the Q-test), a prediction interval for the true outcomes is also provided. Studentized residuals and Cook's distances are used to examine whether studies may be outliers and/or influential in the context of the model. Studies with a studentized residual larger than the 100 x (1 - 0.05/(2 X k))th percentile of a standard normal distribution are considered potential outliers (i.e., using a Bonferroni correction with two-sided alpha = 0.05 for k studies included in the meta-analysis). Studies with a Cook's distance larger than the median plus six times the interquartile range of the Cook's distances are considered to be influential. The rank correlation test and the regression test, using the standard error of the observed outcomes as predictor, are used to check for funnel plot asymmetry.

A total of k=8 studies were included in the analysis. The observed standardized mean differences ranged from -3.7016 to 0.1704, with the majority of estimates being negative (88%). The estimated average standardized mean difference based on the random-effects model was \hat{\mu} = -0.9308 (95% CI: -1.8714 to 0.0099). Therefore, the average outcome did not differ significantly from zero (z = -1.9392, p = 0.0525). According to the Q-test, the true outcomes appear to be heterogeneous (Q(7) = 139.8102, p < 0.0001, tau² = 1.7700, I² = 97.1097%). A 95% prediction interval for the true outcomes is given by -3.7028 to 1.8413. Hence, although the average outcome is estimated to be negative, in some studies the true outcome may in fact be positive. An examination of the studentized residuals revealed that one study (Krajovica) had a value larger than ± 2.7344 and may be a potential outlier in the context of this model. According to the Cook's distances, one study (Krajovica) could be considered to be overly influential. The regression test indicated funnel plot asymmetry (p = 0.0344) but not the rank correlation test (p = 0.1087).

Forest Plot

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Forest Plot

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Forest Plot

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Forest Plot

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Forest Plot

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Forest Plot

[3]

Selection Model Results
EstimateSEp-valueCI Lower BoundCI Upper Bound
0.000.0000.000.0000.000
Note. Error during optimization, select another model type
[3]

 

Publication Bias Assessment
Test Namevaluep
Fail-Safe N212.000< .001
Begg and Mazumdar Rank Correlation-0.5000.109
Egger's Regression-2.1150.034
Trim and Fill Number of Studies0.000.
Note. Fail-safe N Calculation Using the Rosenthal Approach

 

Funnel Plot

[3]

Funnel Plot

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Funnel Plot

[3]

Test of Excess Significance | Significant Findings
  
Observed Number of Significant Findings6
Expected Number of Significant Findings8
Observed Number / Expected Number0.816
[4]

 

Test of Excess Significance | Estimated Power of Tests
MinQ1MedianQ3Max
0.8880.8990.9200.9300.961
Note. Estimated Power of Tests (based on theta = -0.9308)
[4]

 

Test of Excess Significance: p = 0.9785 ( X^2 = NA, df = 1). Limit Estimate: NA (where p = 0.1)

p Curve Plot

Publication bias test p-uniform
Test Statisticp-value
0.0000.990
Note. Error

 

Effect size estimation p-uniform
Effect Size EstimateCI Lower BoundCI upper BoundZp-valueNumber of Significant Studies
0.0000.0000.0000.0000.990-1.000
Note. Error

 

Equivalence Test Plot

[5]

Likelihood Plot

[6]

Outlier and Influential Case Diagnostics

Externally Standardized Residual

DFFITS Values

Cook's Distances

Covariance Ratios

Leave-one-out Tau Estimates

Leave-one-out (residual) Heterogeneity Test Statistics

Hat Values

Weights

Q-Q Plot

Meta-Analysis

need finite 'xlim' values

Random-Effects Model (k = 8)
 EstimateseZpCI Lower BoundCI Upper Bound
Intercept-0.3740.232-1.610.107-0.8290.081
......
Note. Tau² Estimator: Restricted Maximum-Likelihood
[3]

 

Heterogeneity Statistics
TauTau²dfQp
0.6150.3781 (SE= 0.2302 )89.69%9.703.7.00049.823< .001

 

The analysis was carried out using the standardized mean difference as the outcome measure. A random-effects model was fitted to the data. The amount of heterogeneity (i.e., tau²), was estimated using the restricted maximum-likelihood estimator (Viechtbauer 2005). In addition to the estimate of tau², the Q-test for heterogeneity (Cochran 1954) and the I² statistic are reported. In case any amount of heterogeneity is detected (i.e., tau² > 0, regardless of the results of the Q-test), a prediction interval for the true outcomes is also provided. Studentized residuals and Cook's distances are used to examine whether studies may be outliers and/or influential in the context of the model. Studies with a studentized residual larger than the 100 x (1 - 0.05/(2 X k))th percentile of a standard normal distribution are considered potential outliers (i.e., using a Bonferroni correction with two-sided alpha = 0.05 for k studies included in the meta-analysis). Studies with a Cook's distance larger than the median plus six times the interquartile range of the Cook's distances are considered to be influential. The rank correlation test and the regression test, using the standard error of the observed outcomes as predictor, are used to check for funnel plot asymmetry.

A total of k=8 studies were included in the analysis. The observed standardized mean differences ranged from -2.0275 to 0.0193, with the majority of estimates being negative (88%). The estimated average standardized mean difference based on the random-effects model was \hat{\mu} = -0.3738 (95% CI: -0.8288 to 0.0812). Therefore, the average outcome did not differ significantly from zero (z = -1.6103, p = 0.1073). According to the Q-test, the true outcomes appear to be heterogeneous (Q(7) = 49.8227, p < 0.0001, tau² = 0.3781, I² = 89.6939%). A 95% prediction interval for the true outcomes is given by -1.6619 to 0.9143. Hence, although the average outcome is estimated to be negative, in some studies the true outcome may in fact be positive. An examination of the studentized residuals revealed that one study (Krajovica) had a value larger than ± 2.7344 and may be a potential outlier in the context of this model. According to the Cook's distances, one study (Krajovica) could be considered to be overly influential. Neither the rank correlation nor the regression test indicated any funnel plot asymmetry (p = 0.5484 and p = 0.6008, respectively).

Forest Plot

[3]

Forest Plot

[3]

Forest Plot

[3]

Forest Plot

[3]

Forest Plot

[3]

Forest Plot

[3]

Selection Model Results
EstimateSEp-valueCI Lower BoundCI Upper Bound
0.000.0000.000.0000.000
Note. Error during optimization, select another model type
[3]

 

Publication Bias Assessment
Test Namevaluep
Fail-Safe N54.000< .001
Begg and Mazumdar Rank Correlation-0.2140.548
Egger's Regression-0.5230.601
Trim and Fill Number of Studies0.000.
Note. Fail-safe N Calculation Using the Rosenthal Approach

 

Funnel Plot

[3]

Funnel Plot

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Funnel Plot

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Test of Excess Significance | Significant Findings
  
Observed Number of Significant Findings3
Expected Number of Significant Findings8
Observed Number / Expected Number0.444
[4]

 

Test of Excess Significance | Estimated Power of Tests
MinQ1MedianQ3Max
0.7860.8190.8440.8690.905
Note. Estimated Power of Tests (based on theta = -0.3738)
[4]

 

Test of Excess Significance: p = 0.9997 ( X^2 = NA, df = 1). Limit Estimate: NA (where p = 0.1)

p Curve Plot

Publication bias test p-uniform
Test Statisticp-value
0.0000.990
Note. Error

 

Effect size estimation p-uniform
Effect Size EstimateCI Lower BoundCI upper BoundZp-valueNumber of Significant Studies
0.0000.0000.0000.0000.990-1.000
Note. Error

 

Equivalence Test Plot

[5]

Likelihood Plot

[6]

Outlier and Influential Case Diagnostics

Externally Standardized Residual

DFFITS Values

Cook's Distances

Covariance Ratios

Leave-one-out Tau Estimates

Leave-one-out (residual) Heterogeneity Test Statistics

Hat Values

Weights

Q-Q Plot

References

[1] The jamovi project (2021). jamovi. (Version 2.2) [Computer Software]. Retrieved from https://www.jamovi.org.

[2] R Core Team (2021). R: A Language and environment for statistical computing. (Version 4.0) [Computer software]. Retrieved from https://cran.r-project.org. (R packages retrieved from MRAN snapshot 2021-04-01).

[3] Viechtbauer, W. (2010). Conducting meta-analyses in R with the metafor package. Journal of Statistical Software. link, 36, 1-48.

[4] Francis, G. (2013). Replication, statistical consistency, and publication bias. Journal of Mathematical Psychology. link, 57, 153-169.

[5] Lakens, D. (2017). Equivalence tests: A practical primer for t-tests, correlations, and meta-analyses. Social Psychological and Personality Science. link, 1, 1-8.

[6] van Houwelingen, H. C., Zwinderman, K. H., Stijnen, T. (1993). A bivariate approach to meta-analysis. Statistics in Medicine. link, 12, 2273-2284.