Search found 9 matches

by apavlo
Tue Aug 23, 2022 5:35 pm
Forum: Help
Topic: MAJOR -Cooks distance rslts different RR vs OR - bug or math
Replies: 5
Views: 2629

Re: MAJOR -Cooks distance rslts different RR vs OR - bug or

Risk Ratio/Relative Risk (RR) vs Odds Ratio (OR) meta-analysis with random effects (if I recall, it might have been fixed-effects)... If you recall, in MAJOR you get a written output of the results. When I run odds ratio it says that Cooks distance detected 1 outlier study (e.g., Ravi, 2022) when I ...
by apavlo
Tue Aug 23, 2022 9:24 am
Forum: Help
Topic: Subgroup analysis after Meta analysis
Replies: 6
Views: 2848

Re: Subgroup analysis after Meta analysis

So yeah you are kinda screwed there as am I. The only option is to use Cochrane's RevMan, however you are locked to use Dersimonian-Laird estimator (DL) which, as opposed to Restricted ML (REML) is proven to suck with high heterogeneity data and will mistakenly produce significant results when there...
by apavlo
Tue Aug 23, 2022 9:19 am
Forum: Help
Topic: MAJOR -Cooks distance rslts different RR vs OR - bug or math
Replies: 5
Views: 2629

Re: MAJOR -Cooks distance rslts different RR or OR - bug or

Hello Ravi. First, thank you for responding! What I meant was odds ratio (OR) vs relative risk (RR). Not a math expert by any stretch but it seems to me that in essence they are measuring the same thing so the Cooks distance analysis should produce similar results. And if not then I would like to kn...
by apavlo
Mon Aug 22, 2022 5:35 pm
Forum: Help
Topic: Subgroup analysis after Meta analysis
Replies: 6
Views: 2848

Re: Subgroup analysis after Meta analysis

My understanding is that you can't do this with the MAJOR package yet and it is so sad... It also really sucks that you can't unlog the forest plots. It also sucks that online for metafor R there is only an RR or OR example to copy Cochrane's vastly superior forest plot design and not for mean diffe...
by apavlo
Fri Aug 19, 2022 2:09 pm
Forum: Help
Topic: Why do JAMOVI MAJOR results hugely differ from RevMan?
Replies: 5
Views: 8466

Re: Why do JAMOVI MAJOR results hugely differ from RevMan?

That would be amazing if this was added. However team is pushing for publication so september will be too late for the work I am doing at the moment. I've now managed to implement the forest plot in R. Unfortunately I can only create Revman forest plots for OR or RR not for mean difference. It becom...
by apavlo
Fri Aug 19, 2022 2:06 pm
Forum: Help
Topic: MAJOR -Cooks distance rslts different RR vs OR - bug or math
Replies: 5
Views: 2629

MAJOR -Cooks distance rslts different RR vs OR - bug or math

Hello so I get a significant outlier detected with cooks distance when I do OR but not when I do RR. Is this a bug or is there a specific mathematical reason why that is? What should I report?

Regards,

Achilleas
by apavlo
Fri Aug 19, 2022 8:50 am
Forum: Help
Topic: Why do JAMOVI MAJOR results hugely differ from RevMan?
Replies: 5
Views: 8466

Re: Why do JAMOVI MAJOR results hugely differ from RevMan?

I also figured out what estimator RevMan uses: Dersimonean & Laird (DL) whilst I've read a couple of studies which say Restricted Maximum Likelihood is superior to DL. Cool! Now I really want to ditch RevMan. However, I do really like the forest plots from Revman. Someone recreated them in Metaf...
by apavlo
Thu Aug 18, 2022 9:18 pm
Forum: Help
Topic: Why do JAMOVI MAJOR results hugely differ from RevMan?
Replies: 5
Views: 8466

Re: Why do JAMOVI MAJOR results hugely differ from RevMan?

I think I figured it out. It is because its log risk ratio while in Revman its not log risk ratio. I just don't get why jamovi uses log. There is only an option to remove log with odds ratio not risk ratio. And even if I chose odds ratio un-log option it only does this with the stats and not the for...
by apavlo
Thu Aug 18, 2022 3:09 pm
Forum: Help
Topic: Why do JAMOVI MAJOR results hugely differ from RevMan?
Replies: 5
Views: 8466

Why do JAMOVI MAJOR results hugely differ from RevMan?

Why do they differ so much? I've used fixed effects in both A total of k=8 studies were included in the analysis. The observed log risk ratios ranged from -1.5404 to 0.0000, with the majority of estimates being negative (62%). The estimated average log risk ratio based on the fixed-effects model was...